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High body mass inde...
High body mass index, asthma and allergy in Swedish schoolchildren participating in the International Study of Asthma and Allergies in Childhood : phase II
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- Mai, Xiaomei, 1969- (author)
- Linköpings universitet,Pediatrik,Hälsouniversitetet
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- Nilsson, Lennart, 1954- (author)
- Linköpings universitet,Pediatrik,Hälsouniversitetet
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- Axelson, Olav, 1937- (author)
- Linköpings universitet,Yrkes- och miljömedicin,Hälsouniversitetet
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- Bråbäck, Lennart (author)
- Mid-Sweden Research and Development Centre, Sundsvall Hospital, Sweden
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- Sandin, Anna (author)
- Umeå universitet,Pediatrik,Department of Paediatrics, Östersund Hospital, Sweden
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- Kjellman, Max (author)
- Linköpings universitet,Pediatrik,Hälsouniversitetet
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- Björkstén, Bengt (author)
- Karolinska Institutet,Centre for Allergy Research and Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
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(creator_code:org_t)
- 2003
- 2003
- English.
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In: Acta Paediatrica. - 0803-5253 .- 1651-2227. ; 92:10, s. 1144-1148
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Abstract
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- Aim: To assess the relationship between high body mass index (BMI) and asthma and atopic manifestations in 12-y-old children.Methods: The relationship between high BMI and asthma symptoms was studied in 457 sixth-grade children, with (n= 161) and without (n= 296) current wheeze. High BMI was defined as ±75th percentile of gender-specific BMI reference values for Swedish children at 12 y of age; overweight as a subgroup of high BMI was defined as ±95th percentile. Children with a BMI >75th percentile served as controls. Questionnaires were used to assess asthmatic and allergic symptoms, and bronchial hyperresponsiveness was assessed by hypertonic saline provocation tests.Results: Current wheeze was associated with high BMI after adjustment for confounding factors (adjusted OR 1.7, 95% CI 1.0–2.5) and overweight had an even more pronounced effect (adjusted OR 1.9, 95% CI 1.0–3.6). In addition, asthma severity was associated with high BMI, as evaluated by the number of wheezing episodes during the previous 12 mo among the wheezing children (adjusted OR 2.0, 95% CI 1.0–4.0). There was also an association between high BMI and the presence of eczema in wheezing children (adjusted OR 2.2, 95% CI 1.0–4.6). However, high BMI was not significantly associated with hay fever, positive skin prick tests or bronchial hyperresponsiveness.Conclusion: The study confirms and extends a previously observed relationship between BMI and the presence of wheezing and asthma.
Keyword
- MEDICINE
- MEDICIN
Publication and Content Type
- ref (subject category)
- art (subject category)
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